TB-500
1. General Research Description
TB-500 is a synthetic peptide fragment derived from the naturally occurring protein thymosin beta-4. Classified as a short chain peptide, TB-500 represents a specific region of the parent molecule responsible for actin-binding activity. Its streamlined structure allows researchers to isolate and study the functional domain associated with cellular motility, cytoskeletal organization, and tissue-level dynamics within controlled laboratory models.
In research environments, TB-500 is widely utilized to evaluate actin-related pathways, cellular migration behavior, and peptide–protein interactions. Published scientific literature highlights the peptide’s relevance in studying cytoskeletal remodeling, angiogenic signaling patterns, and extracellular matrix communication. TB-500’s biochemical characteristics make it valuable for examining peptide-mediated gene expression modulation, cell-signaling cascades, and structure–activity relationship (SAR) profiles.
Mechanistically, TB-500 has been referenced in scientific research for its ability to interact with G-actin, influence cytoskeletal polymerization, and support cellular response modeling. These properties contribute to its role as a tool for investigating molecular transport, motility mechanisms, and peptide engineering strategies across various experimental frameworks.
2. Storage & Handling
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Store lyophilized TB-500 at –20°C or below
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Keep vials sealed tightly and protected from moisture, heat, and light exposure
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After reconstitution, store the solution at 2–8°C
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Avoid repeated freeze–thaw cycles for optimal peptide stability
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Handle using sterile laboratory technique and proper personal protective equipment
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Designed exclusively for controlled, non-clinical laboratory research settings
3. FAQ
Q: What type of research is TB-500 commonly used for?
A: TB-500 is commonly used in studies involving actin dynamics, cellular migration models, cytoskeletal regulation, and peptide-based structure–activity relationship (SAR) assessment.
Q: How should TB-500 be stored after reconstitution?
A: After reconstitution, TB-500 should be kept at 2–8°C. For extended use, aliquoting and freezing at –20°C is recommended to maintain peptide integrity.
Q: What format does TB-500 come in?
A: TB-500 is supplied as a lyophilized powder in sealed research-grade vials to ensure stability during shipping and storage.
4. Legal Disclaimer
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Not for human consumption
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Not for veterinary use
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Not for medical or diagnostic use
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For laboratory and scientific study only
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No claims of safety, efficacy, or intended therapeutic use
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Buyer assumes all responsibility for proper handling, storage, and usage