NAD+
1. General Research Description
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in all living cells and plays a central role in redox reactions, cellular energy transfer, and metabolic pathway modeling. Structurally, NAD+ consists of two nucleotides joined through their phosphate groups—one containing an adenine base and the other containing nicotinamide. This dual-nucleotide arrangement makes NAD+ a versatile molecule for examining electron-transfer reactions and enzymatic interactions in controlled laboratory environments.
In research settings, NAD+ is extensively studied for its involvement in oxidation–reduction reactions, intracellular signaling networks, and enzymatic processes such as those mediated by sirtuins and dehydrogenases. Scientific literature highlights its relevance in experiments analyzing metabolic flux, mitochondrial function models, gene-regulated enzymatic pathways, and cofactor binding behavior. Because NAD+ participates in both catabolic and anabolic reactions, it serves as a foundational molecule for investigations into cellular metabolism, bioenergetics, and biochemical signal transduction.
NAD+ is also frequently used to explore mechanisms related to DNA repair processes, chromatin remodeling, and protein deacetylation pathways. Its predictable structural properties and well-documented molecular interactions make it an important compound for studying cellular homeostasis, coenzyme kinetics, and metabolic regulatory systems.
2. Storage & Handling
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Store lyophilized NAD+ at –20°C or below
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Keep vials sealed and protected from light, moisture, and elevated temperatures
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After reconstitution, store the solution at 2–8°C
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Avoid repeated freeze–thaw cycles to maintain coenzyme stability
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Use sterile laboratory technique and appropriate protective equipment
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Suitable only for controlled, non-clinical laboratory research applications
3. FAQ
Q: What type of research is NAD+ commonly used for?
A: NAD+ is commonly used in studies involving metabolic pathway modeling, redox reactions, enzymatic catalysis, mitochondrial function, and coenzyme-dependent biochemical processes.
Q: How should NAD+ be stored after reconstitution?
A: After reconstitution, NAD+ should be stored at 2–8°C. For longer-term laboratory use, aliquoting and freezing at –20°C is recommended.
Q: What format does NAD+ come in?
A: NAD+ is supplied as a lyophilized powder in sealed, research-grade vials to ensure optimal stability during storage and transport.
4. Legal Disclaimer
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Not for human consumption
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Not for veterinary use
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Not for medical or diagnostic use
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For laboratory and scientific study only
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No claims of safety, efficacy, or intended therapeutic use
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Buyer assumes all responsibility for proper handling, storage, and use