Kisspeptin-10
1. General Research Description
Kisspeptin-10 is a synthetic decapeptide derived from the endogenous Kisspeptin family, a group of structurally related peptides known for their role in regulating key neuroendocrine pathways. As a 10–amino-acid fragment of the larger Kisspeptin sequence, Kisspeptin-10 retains the core region responsible for receptor binding and signaling activity, making it highly valuable in controlled experimental conditions. Its compact structure offers enhanced stability and predictable behavior during laboratory studies.
Within scientific research, Kisspeptin-10 is frequently utilized to investigate mechanisms involving G-protein–coupled receptors, particularly the GPR54 (KISS1R) receptor. Published literature highlights its involvement in intracellular signaling pathways such as calcium mobilization and phospholipase activation, supporting its use as a model compound for studying neuroendocrine communication. Researchers commonly examine its receptor binding affinity, peptide–receptor interactions, and downstream molecular responses across various experimental models.
Mechanistically, Kisspeptin-10 is referenced in scientific studies exploring signal transduction, gene-expression modulation, and hypothalamic regulation pathways. Its well-characterized sequence and receptor specificity allow investigators to analyze biochemical cascades, peptide engineering strategies, and neuropeptide-driven intracellular dynamics.
2. Storage & Handling
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Store lyophilized Kisspeptin-10 at –20°C or below for optimal stability
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Keep vials sealed tightly and protected from moisture and light
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After reconstitution, store the solution at 2–8°C
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Avoid repeated freeze–thaw cycles to maintain peptide integrity
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Use sterile laboratory technique and appropriate protective equipment
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For non-clinical research use only in controlled laboratory environments
3. FAQ
Q: What type of research is Kisspeptin-10 commonly used for?
A: Kisspeptin-10 is commonly used in studies involving neuropeptide signaling, G-protein receptor activation, intracellular calcium modulation, and structure–activity relationship (SAR) analysis.
Q: How should Kisspeptin-10 be stored after reconstitution?
A: After reconstitution, Kisspeptin-10 should be stored at 2–8°C and used within standard laboratory timeframes. For extended use, aliquoting and freezing at –20°C is recommended.
Q: What format does Kisspeptin-10 come in?
A: Kisspeptin-10 is provided as a lyophilized powder in sealed research-grade vials to ensure stability during storage and shipping.
4. Legal Disclaimer
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Not for human consumption
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Not for veterinary use
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Not for medical or diagnostic use
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For laboratory and scientific study only
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No claims of safety, efficacy, or intended therapeutic application
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Buyer assumes all responsibility for proper handling, storage, and usage